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Thursday, September 6, 2007
What is HGH (Human Growth Hormone)?
The first step in our education is to become familiar with some of the terms and definitions used while discussing Human Growth Hormone. Ready? Let's jump right in...
What is a Hormone?
Hormones are tiny chemical messengers that help our body do different tasks. Hormones are made up of amino acids. Hormones are produced by the endocrine glands and then sent all over the body to stimulate certain activities. For example, Insulin is a well known hormone that helps our body digest food. Our growth, digestion, reproduction and sexual functions are all triggered by hormones.
What is Human Growth Hormone?
Human Growth Hormone (HGH or hGH) is the most abundant hormone produced by the pituitary gland (pituitary is one of the endocrine glands). The pituitary gland is located in the center of the brain. HGH is also a very complex hormone. It is made up of 191 amino acids - making it fairly large for a hormone. In fact, it is the largest protein created by the Pituitary gland.
HGH secretion reaches its peak in the body during adolescence. This makes sense because HGH helps stimulate our body to grow. But, HGH secretion does not stop after adolescence. Our body continues to produce HGH usually in short bursts during deep sleep.
Growth Hormone is known to be critical for tissue repair, muscle growth, healing, brain function, physical and mental health, bone strength, energy and metabolism. In short, it is very important to just about every aspect of our life!
What is Recombinant Growth Hormone (GH)?
Recombinant Growth Hormone is GH that is synthesized in the lab. It is a biosynthetic hormone that is identical to human growth hormone, but it is synthesized in the lab. Creating an exact replicate of HGH was not an easy task.
First scientist needed to isolate HGH. Once they achieved this step they could study the DNA make-up of the protein. Scientist quickly realized making recombinant GH would be no easy task since they had to accurately reproduce a 191 amino acid hormone.I wish I could say it was the quest to help mankind that lead to the invention of recombinant GH, but really it was money!
Pharmaceutical companies knew that there was big money to be made if they could create HGH in a test tube. Scientist from the major drug companies raced to produce the 191 amino acid hormone in a test tube. While Genentech first claimed victory in 1985, it was a short lived success. The recombinant GH they made was a 190 amino acid match - they were one amino acid off from HGH. This left the door open for Eli Lilly, who in 1986 created a 191 amino acid hormone that was an identical match to the HGH produced by the pituitary gland. The drug is called Humatrope and is the most widely used recombinant growth hormone today.
About the author:
This article is originally pulished here: What is HGH (Human Growth Hormone)? Advice-HGH.com provides information, research, and clinical studies on HGH (Human Growth Hormone).
Advice HGH Recommends Sytropin HGH.
Sudha is an internet marketer and enjoys writing on various subjects. For permissions use this article, you can reach him at his SEO Firm.
Diabetes and The Menopause
For a diabetic taking medication, keeping blood sugars at the right level is a balancing act. If sugar levels drop too low, because of not eating enough or at the right times, you suffer a hypoglycemia episode (sometimes called 'hypo' for short). For me, this usually manifests itself as shaking; irritability; sweating and a faint-headed feeling. If you are diabetic and have ever had low-blood sugar you may recognize some of these symptoms, amongst others. A quick 'glucose fix' usually settles it within 5-10 minutes.
Now, compare that to some of the symptoms of starting the menopause:
* Hot flushes [I call them 'power-surges' ;)] - similar to the sweats of a hypo
* Mood swings - akin to the irritability you might experience during a hypo.
It is very easy to mistake the symptoms you are feeling for a diabetic hypo.
When I first started the menopause, I frequently confused waking at 2 a.m. in the morning in a cold sweat as a hypo and took a quick sugar boost to settle myself. That pushed my blood sugar levels up when I didn't need it. Not a good idea!
It was only after visiting my Doctor to talk about these frequent, unexpected hypos I discovered I was starting the menopause (I was in my late 40s, so it was rather unexpected, normally it doesn't occur until early-to-mid 50s).
If you are a lady, with diabetes controlled by medication, and you are in your early 50s and you start having frequent, unexplained hypos - check your sugar levels before 'treating the condition'. And get your Doctor to check your symptoms. You may be confusing symptoms of diabetes and the menopause.
And guys; if your lady normally has great control of her diabetes and suddenly seems to be showing the same symptoms she had when she was getting her diabetes into balance (if you knew her then) please be supportive and understanding, she's going through one hell of an experience, but I promise, she will come through and be her normal, loving and charming self once again.
© 2006 Original work by Carol Ann Bentley
Visit http://www.your-diabetes.com for information on diabetes from a diabetic's viewpoint.
Get your complimentary 86-page Diabetes Control guide, including a 53-page list of carbohydrate values of different foods. http://www.your-diabetes.com/free-diabetes-book-gift.html
The Amazing Benefits of Carotene (Beta Carotene) as a Dietary Supplement
The beta-carotene is in fact famous for the help it gives to human's body. One of the most known claims for beta-carotene is that it prevents cancer and heart disease and can boost our immune system.
Beta Carotene is plentiful in vegetables and fruits. The 600 carotenoids are important for our health and is found in yellow, red, and deep green vegetables and fruits.
Studies shows however that taking supplements for a long duration may in fact cause harm, such as the damage to our liver or increased risk of cancer which can determined only by long, large, well-designed studies.
Large amount of Beta Carotene however can turn your skin slightly yellow or orange-, which is in fact harmless.
Beta-carotene is an antioxidant. Antioxidants help deactivate free radicals, unstable molecules that are by products of cells "burning" oxygen for energy. Free radicals can in fact damage the basic structure of cells and therefore leading to chronic diseases, such as cancer and heart diseases. In addition, it can accelerate the aging process.
However, smokers should not take this the pill of beta-carotene because studies show that smokers have an increase of the risk of lung cancer when they take beta-carotene pills. According to studies, taking Beta Carotene even not on high dose actually has a higher rate of developing lung cancer and higher mortality rate than those taking a placebo. However, the risk is only for smokers who smoked more than a pack per day and who drank more than the average amount of alcohol.
Therefore, the moral lesson here is:
• Do not think that any supplements "can't hurt, might help" or that antioxidants are always beneficial. There is a delicate balance of antioxidants and free radicals in our body. Smoking was a complicating factor with beta carotene but who knows what factor such as sun exposure, alcohol, medication, intense exercise might make supplement X< Y and Z dangerous?
• Don't Smoke
• Don't take Beta Carotene Pills if you smoke or if you are a former smoker, or if you are a heavy drinker.
• Eat a lot of fruits and vitamins- Even if you do not smoke, it is much better to obtain beta-carotene from foods not from the pills. There are no any evidence that beta carotene in foods can cause any danger
Beta Carotene is one of the orange dyes that are found in most green leaves and in carrots. Beta Carotene is a member of family of molecules called carotenoides. Beta Carotene is made up of eight isoprene units, which are cyclised at each end.
Beta Carotene is the pigment that gives carrots, sweet potatoes and other yellow vegetables their yellow coloring. Beta Carotene is also used as a colorant in margarine because the absence of it would only make margarine white.
Almost all beta-carotene in supplements are synthetic consisting of only one molecule that is called all Trans beta-carotene. Natural beta-carotene found in foods is made up of two molecules - all Tran's beta-carotene and 9-cis-beta-carotene.
Beta Carotene s the most potent precursor to vitamin A, but its conversion to vitamin A in the body is limited by a feedback system.
Beta-carotene has two roles in our body. It can indeed be converted into vitamin A if the body needs more of the vitamin. In addition, beta-carotene acts as antioxidants, which protect cells from damage caused by harmful free radicals.
The richest sources of beta carotene are yellow, orange, and green leafy fruits and vegetables such as carrots, spinach, lettuce, tomatoes, sweet potatoes, broccoli, cantaloupe, and winter squash to name a few. The more intense the green, yellow or orange color is, the more beta-carotene it possess.
Cooking makes it easier for beta-carotene to be fully too absorbed by the body does not destroy beta Carotene.
Research shows that diets that are low in beta-carotene and carotenoids can increase the body vulnerability to damage from free radicals. As a result, long-term diets with low in beta-carotene may increase tissue damage from free radical activity and increase risk of chronic disease and cancer. Low in beta-carotene may also lead to the reduction of the effectiveness of the immune system.
Joyce Dietzel writes articles for-your-vitamins.com a website dedicated to Vitamins and Supplements ,Herbs and Minerals
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